By organism › Green plants › Sapindaceae › Allophylus edulis

Observationobservedoriginal resultmeasured

Claim · model-written summary

The lyophilized leaf infusion of Allophylus edulis was rich in total phenols (≤177 mg GAE/g).

Taxon: Allophylus edulisAllophylus edulist0
Organ / stage: Leavest0
Outcome: total phenolse1
Value: ≤177 mg GAE/ge1

Not reportedDirection

Verbatim

t0
“Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves”
✓ located verbatim in the source · title, characters 92–157

e1
“ILAE and its fractions were rich in total phenols (≤177 mg GAE/g)”
✓ located verbatim in the source · abstract, characters 1242–1307

Title

Analysis of Secretory Structures, Chemical Composition, and Anti-Inflammatory Properties of Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves

Sidney Mariano dos Santos; Janaine Alberto Marangoni Faoro; Pedro Cruz de Oliveira Junior; et al. Pharmaceuticals 2025. doi:10.3390/ph18101479

Other claims from this paper (8)

Observation The leaf infusion and its fractions showed potent antioxidant activity.
Observation Histochemical analysis revealed leaf secretory structures in the leaves.
Observation The compound AE-1 showed no hepatotoxic, carcinogenic, mutagenic or cytotoxic effects in silico.
Intervention effect All doses of the leaf infusion ILAE reduced edema, hyperalgesia and leukocyte migration.
Intervention effect All doses of the hydromethanolic fraction HMf reduced edema, hyperalgesia and leukocyte migration.
Intervention effect ILAE at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect HMf at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect AE-1 at 3 mg/kg reduced CFA-induced inflammatory responses.

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

The leaf infusion and its fractions showed potent antioxidant activity.

Taxon: Allophylus edulisAllophylus edulist0
Outcome: antioxidant activitye2

Not reportedDirection

Verbatim

t0
“Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves”
✓ located verbatim in the source · title, characters 92–157

e2
“ILAE and its fractions were rich in total phenols (≤177 mg GAE/g) and showed potent antioxidant activity”
✓ located verbatim in the source · abstract, characters 1242–1346

Title

Analysis of Secretory Structures, Chemical Composition, and Anti-Inflammatory Properties of Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves

Sidney Mariano dos Santos; Janaine Alberto Marangoni Faoro; Pedro Cruz de Oliveira Junior; et al. Pharmaceuticals 2025. doi:10.3390/ph18101479

Other claims from this paper (8)

Observation The lyophilized leaf infusion of Allophylus edulis was rich in total phenols (≤177 mg GAE/g).
Observation Histochemical analysis revealed leaf secretory structures in the leaves.
Observation The compound AE-1 showed no hepatotoxic, carcinogenic, mutagenic or cytotoxic effects in silico.
Intervention effect All doses of the leaf infusion ILAE reduced edema, hyperalgesia and leukocyte migration.
Intervention effect All doses of the hydromethanolic fraction HMf reduced edema, hyperalgesia and leukocyte migration.
Intervention effect ILAE at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect HMf at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect AE-1 at 3 mg/kg reduced CFA-induced inflammatory responses.

Observationobservedoriginal resultmeasured

Claim · model-written summary

Histochemical analysis revealed leaf secretory structures in the leaves.

Taxon: Allophylus edulisAllophylus edulist0
Organ / stage: leafe3
Outcome: leaf secretory structurese3

Not reportedDirection

Verbatim

t0
“Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves”
✓ located verbatim in the source · title, characters 92–157

e3
“Histochemical analysis revealed leaf secretory structures”
✓ located verbatim in the source · abstract, characters 1348–1405

Title

Analysis of Secretory Structures, Chemical Composition, and Anti-Inflammatory Properties of Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves

Sidney Mariano dos Santos; Janaine Alberto Marangoni Faoro; Pedro Cruz de Oliveira Junior; et al. Pharmaceuticals 2025. doi:10.3390/ph18101479

Other claims from this paper (8)

Observation The lyophilized leaf infusion of Allophylus edulis was rich in total phenols (≤177 mg GAE/g).
Observation The leaf infusion and its fractions showed potent antioxidant activity.
Observation The compound AE-1 showed no hepatotoxic, carcinogenic, mutagenic or cytotoxic effects in silico.
Intervention effect All doses of the leaf infusion ILAE reduced edema, hyperalgesia and leukocyte migration.
Intervention effect All doses of the hydromethanolic fraction HMf reduced edema, hyperalgesia and leukocyte migration.
Intervention effect ILAE at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect HMf at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect AE-1 at 3 mg/kg reduced CFA-induced inflammatory responses.

Observationobservedoriginal resultno effectsimulated

Claim · model-written summary

The compound AE-1 showed no hepatotoxic, carcinogenic, mutagenic or cytotoxic effects in silico.

Taxon: Allophylus edulisAllophylus edulist0
Compound: AE-1e4
Outcome: hepatotoxic, carcinogenic, mutagenic, or cytotoxic effectse4
Qualifier: in silicoe4

Not reportedDirection

Verbatim

t0
“Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves”
✓ located verbatim in the source · title, characters 92–157

e4
“AE-1 showed no hepatotoxic, carcinogenic, mutagenic, or cytotoxic effects in silico”
✓ located verbatim in the source · abstract, characters 1407–1490

Title

Analysis of Secretory Structures, Chemical Composition, and Anti-Inflammatory Properties of Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves

Sidney Mariano dos Santos; Janaine Alberto Marangoni Faoro; Pedro Cruz de Oliveira Junior; et al. Pharmaceuticals 2025. doi:10.3390/ph18101479

Other claims from this paper (8)

Observation The lyophilized leaf infusion of Allophylus edulis was rich in total phenols (≤177 mg GAE/g).
Observation The leaf infusion and its fractions showed potent antioxidant activity.
Observation Histochemical analysis revealed leaf secretory structures in the leaves.
Intervention effect All doses of the leaf infusion ILAE reduced edema, hyperalgesia and leukocyte migration.
Intervention effect All doses of the hydromethanolic fraction HMf reduced edema, hyperalgesia and leukocyte migration.
Intervention effect ILAE at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect HMf at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect AE-1 at 3 mg/kg reduced CFA-induced inflammatory responses.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

All doses of the leaf infusion ILAE reduced edema, hyperalgesia and leukocyte migration.

Taxon: Allophylus edulisAllophylus edulist0
Treatment: ILAEe5
Outcome: edema, hyperalgesia, and leukocyte migratione5
Direction: reducede5
Qualifier: All dosese5

Not reportedComparator

Verbatim

t0
“Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves”
✓ located verbatim in the source · title, characters 92–157

e5
“All doses of ILAE and HMf reduced edema, hyperalgesia, and leukocyte migration”
✓ located verbatim in the source · abstract, characters 1492–1570

Title

Analysis of Secretory Structures, Chemical Composition, and Anti-Inflammatory Properties of Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves

Sidney Mariano dos Santos; Janaine Alberto Marangoni Faoro; Pedro Cruz de Oliveira Junior; et al. Pharmaceuticals 2025. doi:10.3390/ph18101479

Other claims from this paper (8)

Observation The lyophilized leaf infusion of Allophylus edulis was rich in total phenols (≤177 mg GAE/g).
Observation The leaf infusion and its fractions showed potent antioxidant activity.
Observation Histochemical analysis revealed leaf secretory structures in the leaves.
Observation The compound AE-1 showed no hepatotoxic, carcinogenic, mutagenic or cytotoxic effects in silico.
Intervention effect All doses of the hydromethanolic fraction HMf reduced edema, hyperalgesia and leukocyte migration.
Intervention effect ILAE at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect HMf at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect AE-1 at 3 mg/kg reduced CFA-induced inflammatory responses.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

All doses of the hydromethanolic fraction HMf reduced edema, hyperalgesia and leukocyte migration.

Taxon: Allophylus edulisAllophylus edulist0
Treatment: HMfe5
Outcome: edema, hyperalgesia, and leukocyte migratione5
Direction: reducede5
Qualifier: All dosese5

Not reportedComparator

Verbatim

t0
“Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves”
✓ located verbatim in the source · title, characters 92–157

e5
“All doses of ILAE and HMf reduced edema, hyperalgesia, and leukocyte migration”
✓ located verbatim in the source · abstract, characters 1492–1570

Title

Analysis of Secretory Structures, Chemical Composition, and Anti-Inflammatory Properties of Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves

Sidney Mariano dos Santos; Janaine Alberto Marangoni Faoro; Pedro Cruz de Oliveira Junior; et al. Pharmaceuticals 2025. doi:10.3390/ph18101479

Other claims from this paper (8)

Observation The lyophilized leaf infusion of Allophylus edulis was rich in total phenols (≤177 mg GAE/g).
Observation The leaf infusion and its fractions showed potent antioxidant activity.
Observation Histochemical analysis revealed leaf secretory structures in the leaves.
Observation The compound AE-1 showed no hepatotoxic, carcinogenic, mutagenic or cytotoxic effects in silico.
Intervention effect All doses of the leaf infusion ILAE reduced edema, hyperalgesia and leukocyte migration.
Intervention effect ILAE at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect HMf at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect AE-1 at 3 mg/kg reduced CFA-induced inflammatory responses.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

ILAE at 30 mg/kg reduced CFA-induced inflammatory responses.

Taxon: Allophylus edulisAllophylus edulist0
Treatment: ILAE (30 mg/kg)e6
Outcome: CFA-induced inflammatory responsese6
Direction: reducede6

Not reportedComparator

Verbatim

t0
“Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves”
✓ located verbatim in the source · title, characters 92–157

e6
“ILAE (30 mg/kg), HMf (30 mg/kg), and AE-1 (3 mg/kg) reduced CFA-induced inflammatory responses”
✓ located verbatim in the source · abstract, characters 1572–1666

Title

Analysis of Secretory Structures, Chemical Composition, and Anti-Inflammatory Properties of Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves

Sidney Mariano dos Santos; Janaine Alberto Marangoni Faoro; Pedro Cruz de Oliveira Junior; et al. Pharmaceuticals 2025. doi:10.3390/ph18101479

Other claims from this paper (8)

Observation The lyophilized leaf infusion of Allophylus edulis was rich in total phenols (≤177 mg GAE/g).
Observation The leaf infusion and its fractions showed potent antioxidant activity.
Observation Histochemical analysis revealed leaf secretory structures in the leaves.
Observation The compound AE-1 showed no hepatotoxic, carcinogenic, mutagenic or cytotoxic effects in silico.
Intervention effect All doses of the leaf infusion ILAE reduced edema, hyperalgesia and leukocyte migration.
Intervention effect All doses of the hydromethanolic fraction HMf reduced edema, hyperalgesia and leukocyte migration.
Intervention effect HMf at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect AE-1 at 3 mg/kg reduced CFA-induced inflammatory responses.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

HMf at 30 mg/kg reduced CFA-induced inflammatory responses.

Taxon: Allophylus edulisAllophylus edulist0
Treatment: HMf (30 mg/kg)e6
Outcome: CFA-induced inflammatory responsese6
Direction: reducede6

Not reportedComparator

Verbatim

t0
“Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves”
✓ located verbatim in the source · title, characters 92–157

e6
“ILAE (30 mg/kg), HMf (30 mg/kg), and AE-1 (3 mg/kg) reduced CFA-induced inflammatory responses”
✓ located verbatim in the source · abstract, characters 1572–1666

Title

Analysis of Secretory Structures, Chemical Composition, and Anti-Inflammatory Properties of Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves

Sidney Mariano dos Santos; Janaine Alberto Marangoni Faoro; Pedro Cruz de Oliveira Junior; et al. Pharmaceuticals 2025. doi:10.3390/ph18101479

Other claims from this paper (8)

Observation The lyophilized leaf infusion of Allophylus edulis was rich in total phenols (≤177 mg GAE/g).
Observation The leaf infusion and its fractions showed potent antioxidant activity.
Observation Histochemical analysis revealed leaf secretory structures in the leaves.
Observation The compound AE-1 showed no hepatotoxic, carcinogenic, mutagenic or cytotoxic effects in silico.
Intervention effect All doses of the leaf infusion ILAE reduced edema, hyperalgesia and leukocyte migration.
Intervention effect All doses of the hydromethanolic fraction HMf reduced edema, hyperalgesia and leukocyte migration.
Intervention effect ILAE at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect AE-1 at 3 mg/kg reduced CFA-induced inflammatory responses.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

AE-1 at 3 mg/kg reduced CFA-induced inflammatory responses.

Taxon: Allophylus edulisAllophylus edulist0
Treatment: AE-1 (3 mg/kg)e6
Outcome: CFA-induced inflammatory responsese6
Direction: reducede6

Not reportedComparator

Verbatim

t0
“Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves”
✓ located verbatim in the source · title, characters 92–157

e6
“ILAE (30 mg/kg), HMf (30 mg/kg), and AE-1 (3 mg/kg) reduced CFA-induced inflammatory responses”
✓ located verbatim in the source · abstract, characters 1572–1666

Title

Analysis of Secretory Structures, Chemical Composition, and Anti-Inflammatory Properties of Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk Leaves

Sidney Mariano dos Santos; Janaine Alberto Marangoni Faoro; Pedro Cruz de Oliveira Junior; et al. Pharmaceuticals 2025. doi:10.3390/ph18101479

Other claims from this paper (8)

Observation The lyophilized leaf infusion of Allophylus edulis was rich in total phenols (≤177 mg GAE/g).
Observation The leaf infusion and its fractions showed potent antioxidant activity.
Observation Histochemical analysis revealed leaf secretory structures in the leaves.
Observation The compound AE-1 showed no hepatotoxic, carcinogenic, mutagenic or cytotoxic effects in silico.
Intervention effect All doses of the leaf infusion ILAE reduced edema, hyperalgesia and leukocyte migration.
Intervention effect All doses of the hydromethanolic fraction HMf reduced edema, hyperalgesia and leukocyte migration.
Intervention effect ILAE at 30 mg/kg reduced CFA-induced inflammatory responses.
Intervention effect HMf at 30 mg/kg reduced CFA-induced inflammatory responses.

Observationobservedoriginal resultmeasured

Claim · model-written summary

The essential oil yield of Allophylus edulis leaves ranged between 0.07% and 0.6% (wet weight) across all samples.

Taxon: Allophylus edulisAllophylus edulist0
Outcome: essential oil yielde0
Value: 0.07% and 0.6% (wet wt.)e0

Verbatim

t0
“Allophylus edulis”
✓ located verbatim in the source · title, characters 86–103

e0
“The essential oil yield in this seasonal variation study consistently ranged between 0.07% and 0.6% (wet wt.) for all samples”
✓ located verbatim in the source · abstract, characters 690–815

Title

Seasonal and geographical variation in the chemical composition of essential oil from Allophylus edulis leaves

Sidney Mariano dos Santos; Claudia Andrea Lima Cardoso; Pedro Cruz de Oliveira Junior; et al. South African Journal of Botany 2023. doi:10.1016/j.sajb.2022.12.013

Other claims from this paper (8)

Allophylus edulis 64 claims

64 claims