Abstract
Plants can detect the quorum sensing (QS) signaling molecules of microorganisms, such as amino acids, fat derivatives and diketopiperazines (DKPs), thus allowing the exchange information to promote plant growth and development. Here, we evaluated the effects of 12 synthesized DKPs on Arabidopsis thaliana roots and studied their underlying mechanisms of action. Results showed that, as QS signal molecules, the DKPs promoted lateral root development and root hair formation in A.thaliana to differing degrees. The DKPs enhanced the polar transport of the plant hormone auxin from the shoot to root and triggered the auxin-responsive protein IAA7/17 to decrease the auxin response factor, leading to the accumulation of auxin at the root tip and accelerated root growth. In addition, the DKPs induced the development of lateral roots and root hair in the A. thaliana root system architecture via interference with auxin receptor transporter inhibitor response protein 1 (TIR1). A series of TIR1 sites that potentially interact with DKPs were also predicted using molecular docking analysis. Mutations of these sites inhibited the phosphorylation of TIR1 after DKP treatment, thereby inhibiting lateral root formation, especially TIR1-1 site. This study identified several DKP signal molecules in the QS system that can promote the expression of auxin response factors ARF7/19 via interactions of TIR1 and IAA7/17 proteins, thus promoting plant growth and development.
Abstract from the paper’s OpenAlex record, shown for indexing and research. Copyright remains with the authors or the publisher. Read at the source ↗
The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.
Claims 9
Claim · model-written summary
DKPs promoted lateral root development and root hair formation to differing degrees.
- Taxon
- A.thaliana
Arabidopsis thalianae0 - Treatment
- DKPse0
- Outcome
- lateral root development and root hair formatione0
- Direction
- promotede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the DKPs promoted lateral root development and root hair formation in A.thaliana to differing degrees”
Claim · model-written summary
DKPs enhanced polar auxin transport from shoot to root.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Organ / stage
- shoot to roote0
- Treatment
- DKPse0
- Outcome
- polar transport of the plant hormone auxine0
- Direction
- enhancede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The DKPs enhanced the polar transport of the plant hormone auxin from the shoot to root”
t0“Arabidopsis thaliana”
Claim · model-written summary
DKPs triggered IAA7/17, decreasing auxin response factor and accumulating auxin at the root tip.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Gene
- IAA7/17e0
- Outcome
- accumulation of auxin at the root tipe0
- Qualifier
- decrease the auxin response factore0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“triggered the auxin-responsive protein IAA7/17 to decrease the auxin response factor, leading to the accumulation of auxin at the root tip”
t0“Arabidopsis thaliana”
Claim · model-written summary
DKPs accelerated root growth.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Treatment
- DKPse1
- Outcome
- root growthe0
- Direction
- acceleratede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“accelerated root growth”
t0“Arabidopsis thaliana”
e1“The DKPs enhanced the polar transport”
Claim · model-written summary
DKPs induced lateral roots and root hair through interference with TIR1.
- Taxon
- A. thalianaArabidopsis thalianae0
- Treatment
- DKPse0
- Gene
- TIR1e0
- Outcome
- development of lateral roots and root haire0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the DKPs induced the development of lateral roots and root hair in the A. thaliana root system architecture via interference with auxin receptor transporter inhibitor response protein 1 (TIR1)”
Claim · model-written summary
Docking predicted potential TIR1 sites interacting with DKPs.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Gene
- TIR1e0
- Outcome
- TIR1 sites that potentially interact with DKPse0
Not reportedComparatorValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“A series of TIR1 sites that potentially interact with DKPs were also predicted using molecular docking analysis”
t0“Arabidopsis thaliana”
Claim · model-written summary
Mutations at predicted sites inhibited TIR1 phosphorylation after DKP treatment.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Treatment
- Mutations of these sitese0
- Gene
- TIR1e0
- Outcome
- phosphorylation of TIR1e0
- Direction
- inhibitede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Mutations of these sites inhibited the phosphorylation of TIR1 after DKP treatment”
t0“Arabidopsis thaliana”
Claim · model-written summary
Mutations at predicted sites inhibited lateral root formation, especially at TIR1-1.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Treatment
- Mutations of these sitese1
- Gene
- TIR1-1e0
- Outcome
- lateral root formatione0
- Direction
- inhibitinge0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“thereby inhibiting lateral root formation, especially TIR1-1 site”
e1“Mutations of these sites”
t0“Arabidopsis thaliana”
Claim · model-written summary
DKP signals promoted ARF7/19 expression via TIR1 and IAA7/17 interactions.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Treatment
- DKPe0
- Gene
- ARF7/19e0
- Outcome
- expression of auxin response factors ARF7/19e0
- Qualifier
- interactions of TIR1 and IAA7/17 proteinse0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“several DKP signal molecules in the QS system that can promote the expression of auxin response factors ARF7/19 via interactions of TIR1 and IAA7/17 proteins”
t0“Arabidopsis thaliana”
The same questions in other papers
climate site · quality: protein · Arabidopsis thaliana (thale cress)Positive and negative results
1 in the opposite direction
- positive
climate site · growth · Arabidopsis thaliana (thale cress)Positive and negative results
3 papers in the same direction as this paper · 2 in the opposite direction
- positive
- positive
- negative
2 papers more in this group
See all 6 papers →loss of function · quality: protein · Arabidopsis thaliana (thale cress)Positive and negative results
7 papers in the same direction as this paper · 1 in the opposite direction
- positive
- no effect
- negative
5 papers more in this group
See all 9 papers →loss of function · growth · Arabidopsis thaliana (thale cress)Positive and negative results
92 papers in the same direction as this paper · 38 in the opposite direction
- positive
- positive
- positive
127 papers more in this group
See all 131 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.