Claim · model-written summary
Silencing AKR1 homologues in Nicotiana benthamiana increased sensitivity to glyphosate.
- Taxon
- Nicotiana benthamiana
Nicotiana benthamianae1 - Treatment
- Silencing AKR1 homologuese1
- Gene
- AKR1e1
- Outcome
- sensitivity to glyphosatee1
- Direction
- increasede1
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
e1“Silencing AKR1 homologues in rice and Nicotiana benthamiana or mutation of AKR1 in yeast and Arabidopsis showed increased sensitivity to glyphosate”
Title
Aldo‐keto reductase enzymes detoxify glyphosate and improve herbicide resistance in plants
Ramu S. Vemanna; Amaranatha Reddy Vennapusa; Murugesh Easwaran; et al. Plant Biotechnology Journal 2016. doi:10.1111/pbi.12632
Other claims from this paper (10)
- Intervention effect Silencing AKR1 homologues in rice increased sensitivity to glyphosate.
- Intervention effect Mutation of AKR1 in Arabidopsis increased sensitivity to glyphosate.
- Intervention effect External application of AKR proteins rescued glyphosate-mediated growth inhibition of cucumber seedlings.
- Observation PsAKR1 and OsAKR1 bind efficiently to glyphosate in docking studies.
- Observation Tobacco transgenic lines expressing PsAKR1 could be regenerated on glyphosate.
- Recommendation AKR can be used as a selectable marker to develop transgenic crops.
- Intervention effect PsAKR1-expressing tobacco showed improved tolerance to glyphosate.
- Intervention effect OsAKRI-expressing rice showed improved tolerance to glyphosate.
- Intervention effect Transgenic tobacco and rice plants showed reduced accumulation of shikimic acid under glyphosate.
- Intervention effect Transgenic tobacco and rice plants showed no change in normal photosynthetic rates.