By organism › Green plants › Lamiaceae › Isodon amethystoides

Observationobservedoriginal resultmeasured

Claim · model-written summary

Amethystoidesic acid (1) is a triterpenoid with an unprecedented 5/6/6/6 tetracyclic skeleton isolated from Isodon amethystoides rhizomes

Taxon: Isodon amethystoidesIsodon amethystoidese1
Organ / stage: rhizomese1
Outcome: tetracyclic skeletone1
Qualifier: unprecedented 5/6/6/6e1

Verbatim

e1
“Amethystoidesic acid ( 1 ), a triterpenoid with an unprecedented 5/6/6/6 tetracyclic skeleton, and six undescribed diterpenoids, amethystoidins A–F ( 2 – 7 ), were isolated from the rhizomes of Isodon amethystoides”
✓ located verbatim in the source · abstract, characters 0–214

Title

Di- and Triterpenoids from the Rhizomes of Isodon amethystoides and Their Anti-inflammatory Activities

Wen-Jing Ren; Chi-Cheng Io; Rong Jiang; et al. Journal of Natural Products 2023. doi:10.1021/acs.jnatprod.2c01136

Other claims from this paper (4)

Observationobservedoriginal resultmeasured

Claim · model-written summary

Six undescribed diterpenoids (amethystoidins A-F) were isolated from Isodon amethystoides rhizomes

Taxon: Isodon amethystoidesIsodon amethystoidese1
Organ / stage: rhizomese1
Outcome: undescribed diterpenoidse1
Value: sixe1

Verbatim

e1
“Amethystoidesic acid ( 1 ), a triterpenoid with an unprecedented 5/6/6/6 tetracyclic skeleton, and six undescribed diterpenoids, amethystoidins A–F ( 2 – 7 ), were isolated from the rhizomes of Isodon amethystoides”
✓ located verbatim in the source · abstract, characters 0–214

Title

Di- and Triterpenoids from the Rhizomes of Isodon amethystoides and Their Anti-inflammatory Activities

Wen-Jing Ren; Chi-Cheng Io; Rong Jiang; et al. Journal of Natural Products 2023. doi:10.1021/acs.jnatprod.2c01136

Other claims from this paper (4)

Observationobservedoriginal resultmeasured

Claim · model-written summary

31 known di- and triterpenoids were isolated along with the new compounds from Isodon amethystoides rhizomes

Taxon: Isodon amethystoidesIsodon amethystoidese1
Outcome: known di- and triterpenoidse2
Value: 31e2

Verbatim

e1
“Amethystoidesic acid ( 1 ), a triterpenoid with an unprecedented 5/6/6/6 tetracyclic skeleton, and six undescribed diterpenoids, amethystoidins A–F ( 2 – 7 ), were isolated from the rhizomes of Isodon amethystoides”
✓ located verbatim in the source · abstract, characters 0–214

e2
“along with 31 known di- and triterpenoids ( 8 – 38 )”
✓ located verbatim in the source · abstract, characters 215–267

Title

Di- and Triterpenoids from the Rhizomes of Isodon amethystoides and Their Anti-inflammatory Activities

Wen-Jing Ren; Chi-Cheng Io; Rong Jiang; et al. Journal of Natural Products 2023. doi:10.1021/acs.jnatprod.2c01136

Other claims from this paper (4)

Intervention effectobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

Compounds 6, 16, 21, 22, 24 and 27 significantly inhibited NO production in LPS-stimulated RAW264.7 cells

Taxon: Isodon amethystoidesIsodon amethystoidest0
Treatment: Compounds 6, 16, 21, 22, 24, and 27e3
Outcome: nitric oxide (NO) productione3
Direction: inhibitede3
Qualifier: lipopolysaccharide (LPS)-stimulated RAW264.7 cellse3

Not reportedComparator

Verbatim

e3
“Compounds 6, 16, 21, 22, 24, and 27 significantly inhibited nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW264.7 cells”
✓ located verbatim in the source · abstract, characters 661–803

t0
“Isodon amethystoides”
✓ located verbatim in the source · title, characters 43–63

Title

Di- and Triterpenoids from the Rhizomes of Isodon amethystoides and Their Anti-inflammatory Activities

Wen-Jing Ren; Chi-Cheng Io; Rong Jiang; et al. Journal of Natural Products 2023. doi:10.1021/acs.jnatprod.2c01136

Other claims from this paper (4)

Mechanismhypothesisoriginal resultpositivemeasured

Claim · model-written summary

Inhibition of NO production may be partly mediated by downregulation of LPS-induced iNOS protein expression

Taxon: Isodon amethystoidesIsodon amethystoidest0
Gene: inducible nitric oxide synthase (iNOS)e4
Outcome: nitric oxide (NO) productione3
Qualifier: could be partly mediatede4

Verbatim

e3
“Compounds 6, 16, 21, 22, 24, and 27 significantly inhibited nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW264.7 cells”
✓ located verbatim in the source · abstract, characters 661–803

e4
“which could be partly mediated by the downregulation of LPS-induced inducible nitric oxide synthase (iNOS) protein expression”
✓ located verbatim in the source · abstract, characters 805–930

t0
“Isodon amethystoides”
✓ located verbatim in the source · title, characters 43–63

Title

Di- and Triterpenoids from the Rhizomes of Isodon amethystoides and Their Anti-inflammatory Activities

Wen-Jing Ren; Chi-Cheng Io; Rong Jiang; et al. Journal of Natural Products 2023. doi:10.1021/acs.jnatprod.2c01136

Other claims from this paper (4)

Observationobservedoriginal resultmeasured

Claim · model-written summary

Isodon amethystoides was among the most commonly used medicines.

Taxon: Isodon amethystoidesIsodon amethystoidese0
Outcome: most commonly used ethnomedicinese0

Verbatim

e0
“Three medicinal plant species, Isodon amethystoides, Asarum insigne, and Acorus tatarinowii, are the most commonly used ethnomedicines”
✓ located verbatim in the source · abstract, characters 2699–2833

Title

Diversity and traditional knowledge of medicinal plants used by Shui people in Southwest China

Sizhao Liu; Beixi Zhang; Qiyi Lei; et al. Journal of Ethnobiology and Ethnomedicine 2023. doi:10.1186/s13002-023-00594-4

Other claims from this paper (10)

Observation Shui healers used parts of 505 plant species medicinally.
Observation Recorded plants comprised 405 genera.
Observation Recorded plants comprised 156 families.
Observation Fabaceae was the most represented family.
Observation Most commonly used medicinal plants were herbaceous.
Observation Shui people typically used whole plants as medicines.
Observation The survey recorded 85 diseases treated by Shui medicinal plants.
Observation Rheumatism and bone fractures were treated by the largest number of plant species.
Observation Asarum insigne was among the most commonly used medicines.
Observation Acorus tatarinowii was among the most commonly used medicines.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

BC inoculation increased Rabdosia biomass by 185.07%.

Taxon: R. amethystoidesIsodon amethystoidese0
Treatment: inoculation with BCe0
Interactor: Bacillus cereusBacillus cereuse1symbiont
Outcome: biomass of R. amethystoidese0
Direction: increasede0
Value: 185.07%e0

Not reportedComparator

Verbatim

e0
“inoculation with BC increased the biomass of R. amethystoides by 185.07%”
✓ located verbatim in the source · abstract, characters 874–946

e1
“Bacillus cereus (BC)”
✓ located verbatim in the source · abstract, characters 527–547

Title

Effects of Septoglomus constrictum and Bacillus cereus on the competitive growth of Ageratina adenophora

Ewei Du; Yaping Chen; Yang Li; et al. Frontiers in Microbiology 2023. doi:10.3389/fmicb.2023.1131797

Other claims from this paper (9)

Intervention effect Bacillus cereus inoculation increased Ageratina biomass by 14.77% during competition with Rabdosia.
Intervention effect Septoglomus constrictum inoculation increased Ageratina biomass by 112.07% during competition.
Intervention effect Combined BC and SC inoculation increased Ageratina biomass by 197.74% during competition.
Intervention effect SC inoculation decreased Rabdosia biomass by 37.31% versus uninoculated treatment.
Intervention effect BC and SC coinoculation decreased Rabdosia biomass by 59.70% versus uninoculated treatment.
Intervention effect BC inoculation increased rhizosphere soil nutrient content for both plants and promoted their growth.
Intervention effect SC inoculation increased nitrogen and phosphorus content of Ageratina, enhancing competitiveness.
Intervention effect SC plus BC inoculation increased nitrogen and phosphorus content of Ageratina, enhancing competitiveness.
Intervention effect Dual SC and BC inoculation increased AMF colonization rate and Bacillus density compared with single inoculation.

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

SC inoculation decreased Rabdosia biomass by 37.31% versus uninoculated treatment.

Taxon: R. amethystoidesIsodon amethystoidese0
Treatment: inoculation with SCe0
Interactor: Septoglomus constrictumSeptoglomus constrictume1symbiont
Outcome: R. amethystoides biomasse0
Direction: decreasede0
Value: 37.31e0
Comparator: uninoculated treatmente0

Verbatim

e0
“inoculation with SC or BC + SC decreased R. amethystoides biomass by 37.31 and 59.70% compared to the uninoculated treatment.”
✓ located verbatim in the source · abstract, characters 954–1079

e1
“Septoglomus constrictum , SC”
✓ located verbatim in the source · abstract, characters 493–521

Title

Effects of Septoglomus constrictum and Bacillus cereus on the competitive growth of Ageratina adenophora

Ewei Du; Yaping Chen; Yang Li; et al. Frontiers in Microbiology 2023. doi:10.3389/fmicb.2023.1131797

Other claims from this paper (9)

Intervention effect Bacillus cereus inoculation increased Ageratina biomass by 14.77% during competition with Rabdosia.
Intervention effect Septoglomus constrictum inoculation increased Ageratina biomass by 112.07% during competition.
Intervention effect Combined BC and SC inoculation increased Ageratina biomass by 197.74% during competition.
Intervention effect BC inoculation increased Rabdosia biomass by 185.07%.
Intervention effect BC and SC coinoculation decreased Rabdosia biomass by 59.70% versus uninoculated treatment.
Intervention effect BC inoculation increased rhizosphere soil nutrient content for both plants and promoted their growth.
Intervention effect SC inoculation increased nitrogen and phosphorus content of Ageratina, enhancing competitiveness.
Intervention effect SC plus BC inoculation increased nitrogen and phosphorus content of Ageratina, enhancing competitiveness.
Intervention effect Dual SC and BC inoculation increased AMF colonization rate and Bacillus density compared with single inoculation.

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

BC and SC coinoculation decreased Rabdosia biomass by 59.70% versus uninoculated treatment.

Taxon: R. amethystoidesIsodon amethystoidese0
Treatment: BC + SCe0
Outcome: R. amethystoides biomasse0
Direction: decreasede0
Value: 59.70%e0
Comparator: uninoculated treatmente0

Verbatim

e0
“inoculation with SC or BC + SC decreased R. amethystoides biomass by 37.31 and 59.70% compared to the uninoculated treatment.”
✓ located verbatim in the source · abstract, characters 954–1079

Title

Effects of Septoglomus constrictum and Bacillus cereus on the competitive growth of Ageratina adenophora

Ewei Du; Yaping Chen; Yang Li; et al. Frontiers in Microbiology 2023. doi:10.3389/fmicb.2023.1131797

Other claims from this paper (9)

Intervention effect Bacillus cereus inoculation increased Ageratina biomass by 14.77% during competition with Rabdosia.
Intervention effect Septoglomus constrictum inoculation increased Ageratina biomass by 112.07% during competition.
Intervention effect Combined BC and SC inoculation increased Ageratina biomass by 197.74% during competition.
Intervention effect BC inoculation increased Rabdosia biomass by 185.07%.
Intervention effect SC inoculation decreased Rabdosia biomass by 37.31% versus uninoculated treatment.
Intervention effect BC inoculation increased rhizosphere soil nutrient content for both plants and promoted their growth.
Intervention effect SC inoculation increased nitrogen and phosphorus content of Ageratina, enhancing competitiveness.
Intervention effect SC plus BC inoculation increased nitrogen and phosphorus content of Ageratina, enhancing competitiveness.
Intervention effect Dual SC and BC inoculation increased AMF colonization rate and Bacillus density compared with single inoculation.

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Native plant growth was greatly suppressed under mixed planting with inoculated Ageratina adenophora.

Taxon: R. amethystoidesIsodon amethystoidese1
Treatment: mixed plantinge0
Interactor: A. adenophoraAgeratina adenophorae1other
Outcome: growth of native plantse0
Direction: suppressede0

Not reportedComparator

Verbatim

e0
“the growth of native plants was greatly suppressed under mixed planting”
✓ located verbatim in the source · abstract, characters 1416–1487

e1
“The effects of these rhizospheric Bacillus communities on the growth and competition of A. adenophora and R. amethystoides were evaluated”
✓ located verbatim in the source · abstract, characters 368–505

Title

Rhizospheric Bacillus-Facilitated Effects on the Growth and Competitive Ability of the Invasive Plant Ageratina adenophora

Ewei Du; Yaping Chen; Yahong Li; et al. Frontiers in Plant Science 2022. doi:10.3389/fpls.2022.882255

Other claims from this paper (9)

Isodon amethystoides 23 claims

23 claims